| Matches by round |
| 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 |
| Match list: | By round By date Latest | Player stats: |
| R | Date | Home | Score | Away | Time | Location | |
| 1 | 11/04/2010 | Peninsula | 3 - 1 | S.E. Wolves | 11:00 | ||
| 2 | 18/04/2010 | S.E. Wolves | 0 - 1 | Westernport | 11:00 | ||
| 3 | 25/04/2010 | S.E. Wolves | 0 - 5 | Baxter Eagles | 11:00 | ||
| 4 | 2/05/2010 | Montrose | 0 - 4 | S.E. Wolves | 11:00 | ||
| 5 | 16/05/2010 | S.E. Wolves | 0 - 5 | Hampton Park U | 11:00 | ||
| 6 | 23/05/2010 | Bye | - | S.E. Wolves | 11:00 | ||
| 7 | 30/05/2010 | Rosebud | 1 - 0 | S.E. Wolves | 11:00 | Olympic Res, Besgrove St | |
| 9 | 20/06/2010 | Bayswater | 1 - 0 | S.E. Wolves | 10:00 | ||
| 10 | 27/06/2010 | S.E. Wolves | 0 - 8 | Peninsula | 11:00 | Westall Secondary College, Fairbank Rd, Clayt | |
| 11 | 11/07/2010 | Westernport | 4 - 1 | S.E. Wolves | 10:30 | Graham Myers Res, Bittern | |
| 12 | 18/07/2010 | Baxter Eagles | 4 - 1 | S.E. Wolves | 11:00 | ||
| 13 | 25/07/2010 | S.E. Wolves | 0 - 1 | Montrose | 11:00 | ||
| 14 | 8/08/2010 | Hampton Park U | 4 - 0 | S.E. Wolves | 11:00 | @ SE Wolves | |
| 15 | 15/08/2010 | S.E. Wolves | - | Bye | 11:00 | ||
| 8 | 22/08/2010 | S.E. Wolves | 0 - 7 | Boronia Maidens | 11:00 | ||
| 16 | 29/08/2010 | S.E. Wolves | 1 - 1 | Rosebud | 11:00 | ||
| 17 | 5/09/2010 | Boronia Maidens | 3 - 0 | S.E. Wolves | 11:00 | ||
| 18 | 12/09/2010 | S.E. Wolves | 1 - 3 | Bayswater | 11:00 |