| Matches by round |
| 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 |
| Match list: | By round By date Latest | Player stats: |
| R | Date | Home | Score | Away | Time | Location | |
| 1 | 11/04/2010 | Westernport | 1 - 3 | Endeavour Strk | 15:00 | ||
| 2 | 18/04/2010 | Rosebud | 1 - 2 | Endeavour Strk | 15:00 | ||
| 3 | 25/04/2010 | Endeavour Strk | 1 - 2 | Croydon Ranges | 15:00 | ||
| 4 | 2/05/2010 | Bayswater Strks | 3 - 1 | Endeavour Strk | 15:00 | ||
| 5 | 16/05/2010 | Endeavour Strk | 4 - 0 | Mornington | 15:00 | ||
| 6 | 23/05/2010 | Endeavour Strk | 3 - 1 | Langwarrin | 15:00 | ||
| 7 | 30/05/2010 | Baxter Eagles | 0 - 2 | Endeavour Strk | 15:00 | ||
| 9 | 20/06/2010 | Hampton Park U | 2 - 2 | Endeavour Strk | 15:00 | ||
| 11 | 11/07/2010 | Endeavour Strk | 5 - 2 | Rosebud | 15:00 | @ Rosebud | |
| 12 | 18/07/2010 | Croydon Ranges | 1 - 1 | Endeavour Strk | 15:00 | ||
| 13 | 25/07/2010 | Endeavour Strk | 0 - 0 | Bayswater Strks | 15:00 | Sweeny Reserve | |
| 14 | 8/08/2010 | Mornington | 3 - 0 | Endeavour Strk | 15:00 | ||
| 10 | 12/08/2010 | Endeavour Strk | 3 - 3 | Westernport | 20:30 | ||
| 15 | 15/08/2010 | Langwarrin | 3 - 2 | Endeavour Strk | 15:00 | ||
| 8 | 22/08/2010 | Endeavour Strk | 3 - 1 | Montrose | 15:00 | Betula Reserve | |
| 16 | 29/08/2010 | Endeavour Strk | 0 - 0 | Baxter Eagles | 15:00 | ||
| 17 | 5/09/2010 | Montrose | 0 - 0 | Endeavour Strk | 15:00 | ||
| 18 | 12/09/2010 | Endeavour Strk | 5 - 1 | Hampton Park U | 15:00 |